ea0073oc15.3 | Oral Communications 15: Late Breaking | ECE2021
Gulde Sebastian
, Martino Daniela De
, Mohr Hermine
, Satam Swapna
, Foscarini Alessia
, Nölting Svenja
, Pellegata Svenja
Pheochromocytoma and Paraganglioma, collectively referred to as PPGLs, are rare, mostly benign neuroendocrine tumors arising from chromaffin cells of the adrenal gland or of extra-adrenal sites, respectively. Surgery is the first-line therapy for localized PPGLs. However, up to 17% of PPGLs show metastatic spread, and for these cases there is no curative treatment. Therefore, the identification of novel therapeutic approaches for advanced PPGLs is highly clinically relevant. W...